Projects
Research projects that I coordinate or take part in. Each card links to the project’s own page, or to its official website where it has one.
Ongoing
OPTISTENT
Designing stents matched to each patient’s anatomy through shape optimisation. The pipeline starts from imaging to reconstruct the geometry of the vessel and the lesion, simulates deployment in FEniCS and SOFA, then evolves the geometry of the device by shape derivation and adjoint methods.
MATH-AmSud NeuralFEM
Designing neural networks that are optimised and certified for non-smooth biomechanical problems, by bringing to them the a priori and a posteriori analysis tools of finite elements. The aim is to guarantee the reliability of the predictions — which current networks lack — on problems with steep gradients, singularities or discontinuities. The consortium brings together 16 researchers from Uruguay, Colombia, Chile and France.
PREMYOM
Slowing the myopia epidemic by personalising myopia-control lenses and the care pathway of young short-sighted patients. The consortium models myopic progression from retinal mechanisms and from a real-world cohort unique in Europe, and builds a digital twin of the myopic eye.
MEDITWIN
A European, sovereign platform of digital twins for healthcare. Virtualising organs and physio-pathological systems from medical data supports clinical decision-making, by predicting how a condition will evolve and how successful the available interventions would be.
ANR JCJC φ-FEM
Turning φ-FEM — a finite element method for domains of complex shape on regular meshes — into a tool for real-time, patient-specific simulation of human organs. The method is adapted to biomechanics, then combined with neural networks and integrated into the SOFA platform.
ANR SKELOID
Understanding keloid fibrosis through a multi-scale in vitro / in vivo / in silico approach. The project models the role of the mechanical and inflammatory factors surrounding the cells, and the interfaces between healthy and pathological tissue, up to digital twins of skin organoids on a chip.
ANR TRECOS
New directions in the control theory of partial differential equations, motivated by ecology and biology: constraints on the controls and the trajectories — positivity, for instance — and controllability of problems involving non-local operators, delay or memory terms.
Completed projects
ICube API φ-FEM
Bringing φ-FEM into Feel++, the open-source C++ finite element library. The method is adapted to the biomechanical setting on regular hexahedral meshes, so as to avoid numerical locking, then extended to material heterogeneity and topology changes.
STIC-AmSud MEMBICA
New strategies for the biological control of arboviruses transmitted by Aedes aegypti and Aedes albopictus: the sterile insect technique, transgenic mosquitoes, infection with Wolbachia. The question is how to carry out releases at large scale so as to maximise their effect.